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The Unified Huntington's Disease Rating Scale\u2010Total Motor Score (UHDRS\u2010TMS) is a clinician\u2010rated scale that was developed by the Huntington Study Group to prospectively assess clinical features of HD in both patients with HD and individuals at risk for HD.
Is Huntington disease hereditary?
Huntington's disease is a condition that stops parts of the brain working properly over time. It's passed on (inherited) from a person's parents.
How do you test for chorea?
How is chorea diagnosed? Blood tests to check for infections, lupus, thyroid levels or other endocrine or metabolic abnormalities. Imaging studies such as magnetic resonance imaging (MRI) scan or a computed tomography (CT) scan to look for changes in your brain.
Does Huntington's disease run in families?
Who does Huntington's disease (HD) affect? Although anyone can develop HD, it tends to run in people of European descent (having family members who came from Europe). But the main factor is whether you have a parent with HD. If you do, you have a 50% chance of also having the disease.
What is the scale for Huntington's disease?
The items are rated from zero to four, with zero indicating normal findings and four indicating severe abnormalities. The range of the Total Motor Score (TMS) is 0 to 124, with higher scores indicating more severe motor impairment.
Which parent carries the gene for Huntington's disease?
There have been reports that juvenile onset Huntington's chorea is almost always inherited from the father, and that late-onset Huntington's chorea is inherited more often from the mother than from the father.
What is the total maximal chorea score?
The total maximal chorea score is a standardized, reliable chorea assessment based on frequency and severity in 7 body regions, with a range of 0 to 28.
What is Uhdrs TMS?
The Unified Huntington's Disease Rating Scale\u2010Total Motor Score (UHDRS\u2010TMS) is a clinician\u2010rated scale that was developed by the Huntington Study Group to prospectively assess clinical features of HD in both patients with HD and individuals at risk for HD.
What is the scale for Huntington's disease?
The items are rated from zero to four, with zero indicating normal findings and four indicating severe abnormalities. The range of the Total Motor Score (TMS) is 0 to 124, with higher scores indicating more severe motor impairment.
What does Uhdrs measure?
The UHDRS is a standardized rating system used to quantify the severity of HD. Used clinically and in research, it measures the patient's abilities in four general areas: motor, cognitive, behavioral, and functional.
uhdrs scale
PREDICT-HD Huntington Disease Study - NCBI
View pdf copy of original document. Modified Unified Huntington's Disease Rating Scale '99 (UHDRS). PREDICT-HD. MODIFIED UNIFIED HUNTINGTON'S DISEASE RATING ...
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