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Methadone is a synthetic (man-made) narcotic. It is used legally to treat addiction to narcotics and to relieve severe pain, often in individuals who have cancer or terminal illnesses.
Federal regulations mandate that the initial dose should not surpass 30 mg, and the total dose on the first day should not exceed 40 mg. For individuals with minimal or no opioid tolerance, reinitiating methadone after a relapse is advisable at a lower dose range of 2.5 to 10 mg.
Among the changes, doctors would be allowed to prescribe patients up to 72 hours worth of methadone that they can take home. The amount of methadone a patient could take home would also be increased, allowing them to avoid lining up for treatment on a daily basis.
Diphenhydramine, for example, which is found in common OTC antihistamines like BENADRYL, occasionally displays like methadone on a drug test. Drugs with sleep aids like Tylenol PM or Advil PM can also present a false-positive result.
In addition the label of each unit dose of methadone, i.e. drink or carry, must include: The total dose in mg of methadone contained in the bottle; A notation: Drink entire contents of bottle; The date for ingestion for carries; Keep refrigerated auxiliary label for carries; and one of the following auxiliary
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Determine the volume of methadone spilled as accurately as possible and enter this quantity in the Supplied column of the methadone register; ensure this is signed by a witness and the person who caused the methadone loss and adjust the balance ingly.

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