Dea 254 csos 2025

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The DEA, Office of Diversion, E- commerce Section, operates the Controlled Substance Ordering System (CSOS) whose purpose is to issue and revoke digital signatures to DEA Registrants (manufactures, distributors, and pharmacies who order controlled substances) to digitally sign electronic orders for controlled
Drug Enforcement Administration (DEA) Office of Diversion Controlled Substance Ordering System (CSOS)
The Principal Coordinator shall serve as an organizations primary CSOS correspondence with regards to CSOS Certificate applications, renewals, and revocations for the DEA Registration(s) identified on their application. The Principal Coordinator applicant may be any individual employed by the organization.
CSOS Coordinators A CSOS Coordinator may be any individual in the DEA Registrants organization and must have their CSOS request approved by the Registrant. Only one Principal Coordinator and one Alternate Coordinator may be enrolled in CSOS for any one DEA Registration number.
A CSOS Power of Attorney (POA) is any individual with the authority to sign controlled substance orders for a DEA Registrant. The CSOS POA applicant must have their request approved by the CSOS Coordinator for the DEA Registration number(s) being applied for.
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A CSOS Certificate is a digital identity issued by the DEAs CSOS Certification Authority (CSOS CA) that allows for electronic ordering for Schedule I and II (as well as III-V) controlled substances. A CSOS Certificate is the digital equivalent of the identification information contained on a DEA Form-222.

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