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Common symptoms that typically develop within 1 week of infection include fever, headache, malaise, nausea, or vomiting. Many rickettsioses also are accompanied by a maculopapular, petechial, or vesicular rash, or sometimes an eschar (a dark necrotic scab) at the site of the tick or mite bite (see Sec.
Most symptomatic rickettsial diseases cause moderate illness, but others, including RMSF (also called Brazilian spotted fever), epidemic typhus, scrub typhus, and Mediterranean spotted fever, can be life-threatening in some cases, particularly when treatment is delayed. Rickettsial Diseases | CDC Yellow Book 2024 cdc.gov yellowbook infections-diseases cdc.gov yellowbook infections-diseases
Long-term Health Problems Some patients who recover from severe RMSF may be left with permanent damage, including amputation of arms, legs, fingers, or toes (from damage to blood vessels in these areas); hearing loss; paralysis; or mental disability. Signs and Symptoms | Rocky Mountain Spotted Fever (RMSF) cdc.gov rmsf symptoms cdc.gov rmsf symptoms
Rocky Mountain spotted fever (RMSF), a tickborne infection caused by Rickettsia rickettsii and characterized by a rash (Figure), has a case-fatality rate as high as 30% in certain untreated patients (1). Even with treatment, hospitalization rates of 72% and case-fatality rates of 4% have been reported (1--3). Fatal Cases of Rocky Mountain Spotted Fever in Family Clusters cdc.gov mmwr preview mmwrhtml cdc.gov mmwr preview mmwrhtml
Without prompt antibiotic treatment, mortality rates are as high as 20 to 30 percent. Rocky Mountain Spotted Fever (Rickettsia rickettsii) - NCBI National Institutes of Health (.gov) books NBK430881 National Institutes of Health (.gov) books NBK430881
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Early treatment of rickettsial infections can prevent complications from developing, reduce the risk of dying, and shorten the recovery time. Rickettsial infections respond promptly to early treatment with the antibiotics (doxycycline preferred).
One group of bacteria ticks carry is called rickettsiae. Thats why these tick-borne conditions are called rickettsial diseases. But not all diseases that ticks carry are rickettsial. For instance, Lyme disease is caused by a different bacteria called Borrelia burgdorferi.
When left untreated, the bacteria can cause damage to blood vessels throughout the body leading to organ and tissue damage. RMSF can be fatal, even in previously healthy people. If not treated correctly, death can often occur within eight days of symptoms starting.

wv dhhr rickettsial infectious disease