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The news clip referenced an experimental vaccine created by New York-based company MimiVax thats designed to delay the progression of glioblastoma. The vaccine is called SurVaxM and targets a protein found in glioblastoma tumors called survivin.
Experimental vaccine shows promise in delaying the return of aggressive brain tumor. The vaccine, called SurVaxM, was shown to nearly double the survival time in a trial of 63 patients. Researchers now hope to confirm the findings in a larger trial.
There are vaccines that treat existing cancer, called treatment vaccines or therapeutic vaccines. These vaccines are a type of cancer treatment called immunotherapy. They work to boost the bodys immune system to fight cancer. Doctors give treatment vaccines to people who already have cancer.
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Developing a personalized cancer vaccine requires the highest precision in identifying somatic variants, as well as in the subsequent prediction and selection of neoantigens for vaccine design. CeGaT CancerNeo identifies somatic alterations through comparative analysis of tumor and normal tissue.
DCVax is a dendritic cell vaccine for treating a wide variety of cancers, including GBM. Fourteen years after it first occurred to Liau to treat GBM with dendritic cells loaded with brain tumor antigens, DCVax is now being tested in a multicenter phase 2 trial.