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Evidence suggests that sucralfate the active ingredient in Carafate heals the gut lining and protects it from further damage due to gastritis.
Take this medication by mouth with a glass of water. Follow the directions on the prescription label. This medication works best if you take it on an empty stomach, 1 hour before meals. Take your doses at regular intervals.
Abstract. Sucralfate is a cytoprotective drug widely used in clinical practice to prevent or treat several gastrointestinal diseases such as gastro-esophageal reflux, gastritis, peptic ulcer, stress ulcer and dyspepsia.
Carafate is an anti-ulcer medication. Carafate is not greatly absorbed into the body through the digestive tract. It works mainly in the lining of the stomach by sticking to ulcer sites and protecting them from acids, enzymes, and bile salts. Carafate is used to treat an active duodenal ulcer.
SUCRALFATE (SOO kral fate) treats stomach ulcers. It works by helping to form a barrier over the ulcer, which protects it from stomach acid and allows it to heal.
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Sucralfate (complex salt of sucrose aluminum hydroxide and sulfate) has a positive charge and binds to the negative charge of the ulcer base to form a gel, which acts to effectively plug the ulcer base and to prevent worsening of the gastritis.
Carafate and omeprazole belong to different drug classes. Carafate is an anti-ulcer drug and omeprazole is a proton pump inhibitor (PPI).
If needed, antacids may be taken along with this medication. If you are also taking sucralfate, take omeprazole at least 30 minutes before sucralfate. Use this medication regularly to get the most benefit from it. To help you remember, take it at the same time each day.
How long does it take for Carafate to work for gastritis? Carafate may take 12 weeks to start healing an inflamed stomach. People should continue the medication for 48 weeks, depending on their doctors advice.
Our advice is always to take the proton pump inhibitor before the sucralfate and wait for an hour so that absorption is not affected.

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