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One accepted protocol is to perform 1-1.5 total plasma volume exchanges with albumin replacement daily or every other day. Usually a minimum of nine to 10 procedures is followed by tapering which is determined on a case by case basis.
A: There is no set number of plasma exchanges performed, although typically patients receive between three and seven exchanges, each of which takes 2-4 hours. The number of treatments can be guided by the clinical recovery, or sometimes a preset number of exchanges are performed.
Plasma exchange may be repeated, but other medications should control most symptoms, eliminating the need for multiple courses of plasmapheresis.
Plasmapheresis can be accomplished through centrifuge-based platforms such the Cobe Spectra, Fenwal Aurora, and the Fresenius COM. TEC series of devices. Patients require either a double-lumen central venous catheter or two large-bore antecubital peripheral lines.
What happens during plasmapheresis and plasma exchange? Providers insert a needle or intravenous line into your arm or central line catheter. They gradually remove small amounts of blood. They use a machine to separate your plasma from your blood. They discard your plasma.
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Two considerably different techniques are commonly used to perform plasmapheresis, including centrifugation and filtration. During centrifugation plasmapheresis, whole blood is spun in order to separate the four major components of blood into layers, ing to their dissimilar densities.
How is plasmapheresis administered? During plasmapheresis donation, you will rest on a cot. Then a needle or catheter will be placed into a vein in the crux of whichever arm has the most robust artery. In some cases, a catheter is placed in the groin or shoulder.

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