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C. elegans contains a primordial p53 gene, cep-1 (C. elegans p53), that is necessary for DNA damage-induced apoptosis and acts as a transcription factor (Derry et al., 2001, Schumacher et al., 2001).
usually measured by a missiles circular error of probability (CEP) and bias. CEP uses the mean point of impact of missile test firings, usually taken at maximum range, to calculate the radius of a circle that would take in 50 percent of the impact points.
Title: Impaired p53/CEP-1 is associated with lifespan extension through an age-related imbalance in the energy metabolism of C. elegans. This work reveals an ancestral function for the p53 family in ensuring the fidelity of meiosis and establishes CEP-1 as a critical determinant of repair pathway choice.
Congenital Erythropoietic Porphyria (CEP) is a very rare inherited metabolic disorder resulting from the deficient function of the enzyme uroporphyrinogen lll cosynthase (UROS), the fourth enzyme in the heme biosynthetic pathway.
CEP allows the nations highest poverty schools and districts to serve breakfast and lunch at no cost to all enrolled students without collecting household applications.

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C-TERMINALLY ENCODED PEPTIDE (CEP) and cytokinin hormones act over short and long distances to control plant responses to environmental cues.
Title: CEP-1, the Caenorhabditis elegans p53 homolog, mediates opposing longevity outcomes in mitochondrial electron transport chain mutants. This review summarizes major advances in understanding of the TP53 family using C. elegans as a model organism.

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