A Real-World Approach to Insulin Therapy 2025

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Examples of these insulins are glargine (Lantus, Basaglar, others), detemir (Levemir), degludec (Tresiba) and NPH (Humulin N, Novolin N, others). Intermediate-acting insulin lasts about 12 to 18 hours. Long-acting insulin works for about 24 hours. And ultralong-acting insulin lasts about 36 hours or longer.
Insulin taken in large doses will cause symptoms of hypoglycemia in the patient. Some of these symptoms include headache, dizziness, palpitations, sweating, abdominal pain, and blurred vision. The immediate therapy for such patients is increasing the levels of glucose.
The discovery of insulin in Toronto in 1921, now 100 years ago, was nothing less than a miracle. It quite rightly stands out as one of the most significant accomplishments of modern medicine and has undoubtedly saved the lives of millions of people now able to live with diabetes.
Incorrect administration of insulin (e.g., too little, too much, or at the wrong times) can result in both transient and serious hypo- and hyperglycemia, wide glycemic excursions, severe hypoglycemia, and DKA.
Hypoglycemia is, by far, the most common adverse effect of insulin therapy. [21] The other adverse effects of insulin therapy include weight gain and rarely electrolyte disturbances like hypokalemia, especially when used along with other drugs causing hypokalemia.
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The most common types of medication error associated with insulin were drug omission (24.7%) followed by wrong-drug errors (13.9%).
Common insulin side effects include hypoglycemia (low blood glucose), injection site reactions, and weight gain. Rare side effects of insulin are lipodystrophy (abnormal distribution) and swelling in the arms and legs. Its important to check your blood glucose regularly while taking insulin.
Ways to Take Insulin There are different insulin delivery methods available: Insulin syringe -- insulin is drawn from a vial into a syringe. Using the needle, you inject the insulin under the skin. Insulin pen -- disposable insulin pens have prefilled insulin delivered under the skin using a replaceable needle.

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