V940 2025

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2019 4.8 Satisfied (181 Votes)
2019 4.2 Satisfied (118 Votes)
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mRNA-4157/V940 is designed to stimulate an immune response by generating specific T cell responses based on the unique mutational signature of a patients tumor. KEYTRUDA is an immunotherapy that works by increasing the ability of the bodys immune system to help detect and fight tumor cells.
Fatal adverse reactions occurred in 8% of patients who received KEYTRUDA including infection (2.3%) and thromboembolism (1.3%). KEYTRUDA was permanently discontinued due to adverse reactions in 15% of patients.
Adults and children may have some side effects from a COVID-19 vaccine, including pain, redness or swelling at the injection site, tiredness, headache, muscle pain, chills, fever, and nausea. These side effects typically resolve after a few days. Serious side effects are rare but may occur.
Potential cancer vaccine-related side effects may result from a misdirected immune response where the immune system targets healthy cells that express the same target proteins.
mRNA-4157/V940 is an mRNA based cancer vaccine. When administered, it will produce one of several dozen possible abnormal proteins commonly found in cancerous tissues. The production of those proteins is intended to invoke an immune response.

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The most common side effects of V940 we know about so far include: tiredness (fatigue) high temperatures (fever) chills, a cough and body aches (flu-like illness) feeling sick. joint and muscle pain. headache. skin rash, warmth, swelling, redness and pain at the site of injection. loss of appetite.
The most common adverse events attributed to mRNA-4157 (V940) in combination with KEYTRUDA were fatigue (60.6%), injection site pain (56.7%), and chills (49.0%). The majority of the adverse events attributed to mRNA-4157 (V940) were Grade 1-2, with fatigue being the most common Grade 3 event and no Grade 4-5 events.

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