Assessment of the incorporation of CNV surveillance into 2026

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Patients with myopic CNV usually respond rapidly to treatment, and recurrence is much less frequent than in other neovascular disorders such as AMD.
A variety of technologies are available to detect CNVs such as fluorescence in situ hybridization (FISH), Array-comparative genomic hybridization (aCGH) (see Unit 4.14), genome-wide single nucleotide polymorphism (SNP) arrays (see also Unit 8.13), and most recently, high-throughput sequencing.
Most CNVs are harmless; however, some are associated with human diseases including neurodevelopmental disorders. Hundreds of CNVs have been linked to neurological phenotypes, including autism, schizophrenia, and bipolar disorder.
Introduction to CNV Analysis Copy number variations (CNVs) are genomic alterations that result in an abnormal number of copies of one or more genes. Structural genomic rearrangements such as duplications, deletions, translocations, and inversions can cause CNVs.

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