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FRAT Laboratory Test Form - Iliad Neurosciences Inc

FRAT Laboratory Test Form - Iliad Neurosciences Inc 2025

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The document is a specimen identification form for FRAT testing by Iliad Neurosciences, Inc. It includes sections for facility and patient information, consent for testing, payment details, and physician acknowledgment. The form emphasizes the importance of not taking certain medications prior to blood draw and outlines the cost of the test.

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We have answers to the most popular questions from our customers. If you can't find an answer to your question, please contact us.

What does a positive frat test mean?

Those that are positive for either of the two autoantibodies detected by the FRAT are treated with leucovorin by slowly increasing the dose over two to four weeks. In our clinical trials we have found improvements in many symptoms, most pronounced language, but also disruptive behavior, within three to four months.

How long does a frat test take?

How long does FRAT take to perform and when can I expect results? The assays are not simple to perform, and each assay takes five to seven days, because of the need for overnight incubations. Turn-around time is generally 2 to 4 weeks for reports to be sent to your physician.

How to do a FRAT test?

Blood Sample Collection and Shipping Draw 24 ml of blood into a red-top tube or SST tube (serum). Please note that the FRAT kit contains SST tubes. If feasible: Remove red cells by centrifugation, transfer serum/plasma to clean tube and refrigerate (4C) or freeze (-20C) until time of shipping.

How to treat folate receptor autoantibodies?

High dose folinic acid (0.52 mg/kg body weight) has been shown to bypass these antibodies and improve verbal communication in children with autism. Parents have the option to test for the presence of folate receptor antibodies through a blood draw or do a trial of high dose folinic acid.

What is a FRAT test?

This blood test measures the presence of autoantibodies to the folate receptor alpha (FRa). If autoantibodies are present, then there is an indication that folate (vitamin B9) is not being properly distributed across the blood brain barrier and into the Cerebrospinal Fluid (CSF).

What does the FRAT test test for?

FRAT (Folate Receptor Autoantibody Test) measures the presence of autoantibodies against the folate receptor alpha (FRa) protein. Folate receptor autoantibodies can interfere with folate (vitamin B9) transport into the brain, potentially leading to neurological symptoms and developmental delays.

FRAT Laboratory Test Form - Iliad Neurosciences Inc 2025

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