Folate Receptor Autoantibody Test (FRAT Test) 2026

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  1. Click ‘Get Form’ to open the Folate Receptor Autoantibody Test (FRAT Test) in the editor.
  2. Begin by affixing the specimen identification label at the top of the form. Ensure that all patient details are accurate.
  3. In the TEST INFORMATION section, fill in the date and time of specimen collection, along with any relevant diagnosis codes. Remember to note that patients must not take folinic acid or 5-MTHF for 48 hours prior to blood draw.
  4. Complete the FACILITY INFORMATION section with provider and facility details, including NPI number and contact information.
  5. In PATIENT INFORMATION, enter the patient's first name, last name, date of birth, gender, and contact details. If applicable, provide information for a responsible party.
  6. Select a preferred payment method in the PAYMENT INFORMATION section and fill out necessary billing details.
  7. Finally, ensure that both patient consent and provider acknowledgment sections are signed and dated before submission.

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FRAT: A blood test that screens for folate receptor autoantibodies, indicating a potential impediment in folate transport to the brain.
The folate blood test checks for levels of folate in your blood and red blood cells. Low folate can prevent your red blood cells from developing normally and can cause nerve damage. Your folate levels can be affected by different conditions or medicines, and your diet.
This blood test measures the presence of autoantibodies to the folate receptor alpha (FRa). If autoantibodies are present, then there is an indication that folate (vitamin B9) is not being properly distributed across the blood brain barrier and into the Cerebrospinal Fluid (CSF).
FRAT (Folate Receptor Autoantibody Test) measures the presence of autoantibodies against the folate receptor alpha (FRa) protein. Folate receptor autoantibodies can interfere with folate (vitamin B9) transport into the brain, potentially leading to neurological symptoms and developmental delays.
Autoimmune problems can cause the body to produce Folate Receptor Autoantibodies (FRAAs). These FRAAs block the transport of folate into the cerebral spinal fluid. FRAAs are being found at an alarming rate in children with autism. 71% of people with autism have autoantibodies that block folate from getting in the cell.

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People also ask

How long does FRAT take to perform and when can I expect results? The assays are not simple to perform, and each assay takes five to seven days, because of the need for overnight incubations. Turn-around time is generally 2 to 4 weeks for reports to be sent to your physician.
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