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The Mo-99 produced using this reaction has a low specific activity (1-10 Ci/g), slightly higher than that produced from neutron activation of Mo-98, namely reaction (2). Reaction (5) produces Tc-99m directly using protons (p) to remove neutrons (n) from the nuclei of Mo-100 atoms.
Tc-99m is used for the detection of disease and for the study of organ structure and function. Tc-99m is especially useful for nuclear medicine procedures because it can be chemically incorporated into small molecule ligands and proteins that concentrate in specific organs or tissues when injected into the body.
The world supply of 99Mo comes from only five nuclear research reactors and availability has been much reduced in recent times owing to problems at the largest reactors. In the short-term there are limited actions that can be taken owing to capacity issues on alternative imaging modalities.
Molybdenum-99 (Mo-99) is the radioactive isotope that enables many diagnostic nuclear medicine procedures such as SPECT scans, which can detect many potentially life-threatening conditions and help patients receive the potentially life-saving treatments they need.
As they decay, unstable isotopes expel energy in the form of excess alpha, beta, neutron, or photon radiation in order to reach a more stable form. Molybdenum-99 emits beta radiation, or the release of an energized electron from the atomic nucleus, as it decays into its daughter isotope, technetium-99m.
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~900 Ci of 99Mo at reactor discharge having a specific activity of~-,60,000 Ci/g molyb- denum. Subsequent decay of the 99Mo during the recovery and purification procedure reduces the specific activity to ~20,000 Ci/g molyb- denum.

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