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The world supply of 99Mo comes from only five nuclear research reactors and availability has been much reduced in recent times owing to problems at the largest reactors. In the short-term there are limited actions that can be taken owing to capacity issues on alternative imaging modalities.
The Mo-99 produced using this reaction has a low specific activity (1-10 Ci/g), slightly higher than that produced from neutron activation of Mo-98, namely reaction (2). Reaction (5) produces Tc-99m directly using protons (p) to remove neutrons (n) from the nuclei of Mo-100 atoms.
Sr-90 is a beta emitter (546 KeV, no gammas) with a half-life of 28.1 years [specific activity 5217 becquerels/gram (Bq/g), or 141 curies (Ci)/g], Sr-89 is a beta emitter (1.463 MeV, gammas very rarely) with a half-life of 52 days (specific activity 28,200 Ci/g).
Molybdenum-99 (Mo-99) is the radioactive isotope that enables many diagnostic nuclear medicine procedures such as SPECT scans, which can detect many potentially life-threatening conditions and help patients receive the potentially life-saving treatments they need.
Molybdenum-99 emits beta radiation, or the release of an energized electron from the atomic nucleus, as it decays into its daughter isotope, technetium-99m.
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Tc-99m is used for the detection of disease and for the study of organ structure and function. Tc-99m is especially useful for nuclear medicine procedures because it can be chemically incorporated into small molecule ligands and proteins that concentrate in specific organs or tissues when injected into the body.
The half-life and specific activity of 99Tc were redetermined by measuring the activity of a known weight (determined coulometrically) of 99Tc by a liquid scintillation method and found to be 214(0. 05) 105 years and 375(011) 104 disintegration/min per g respectively.

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