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Why cytogenetic analysis is important?

Cytogenetic analysis provides a genome-wide snapshot of an individual's chromosomes by the process of pairing and arranging all of them in an order, and can reveal changes in chromosome numbers (aneuploids) and more delicate structural changes (chromosomal deletions, duplications, translocations and inversions) in the ...

Why is karyotyping important in medical genetics?

Karyotyping is a test to examine chromosomes in a sample of cells. This test can help identify genetic problems as the cause of a disorder or disease.

What are the indications for chromosomal analysis?

Dysmorphic features and/or developmental delay. Fetal or neonatal death with multiple congenital abnormalities or dysmorphic features.

What is the importance of cytogenetics in medical science?

Cytogenetics plays a key role in the detection of chromosomal abnormalities associated with malignancies, as well as the characterization of new alterations that allow more research and increase knowledge about the genetic aspects of these diseases.

What is the preferred specimen for cytogenetic study?

Villi are specimen of choice, but amniotic fluid is acceptable; Uniquely identify twins. Collect 1 cm² placenta by sterile procedure, and place in 50ml tube with transport media (provided by the cytogenetics lab). Maintain at room temperature or refrigerate if sample cannot be delivered within 24 hours.

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What is the importance of cytogenetics in medical technology?

Cytogenetics plays a key role in the detection of chromosomal abnormalities associated with malignancies, as well as the characterization of new alterations that allow more research and increase knowledge about the genetic aspects of these diseases.

Why cytogenetic analysis is important?

Cytogenetic analysis provides a genome-wide snapshot of an individual's chromosomes by the process of pairing and arranging all of them in an order, and can reveal changes in chromosome numbers (aneuploids) and more delicate structural changes (chromosomal deletions, duplications, translocations and inversions) in the ...

What are indications for cytogenetic analysis?

The main indications of cytogenetic studies in congenital genetic diseases are: Abnormal ultrasound findings. Abnormal biochemistry results. Recurrent miscarriages.

What are the main concerns of cytogenetics?

Cytogenetics is \u201cthe branch of genetics that is concerned primarily in cellular components, especially chromosomes, in relation to heredity, genetic anomalies, and pathologic conditions.

What cells are used for cytogenetic analysis?

A cytogenetic test can be obtained for fetal diagnostic testing as early as 10 weeks of gestation from chorionic villus sampling (CVS), using trophoblast cells or cultured mesenchymal cells. By analyzing cells cultured from amniotic fluid, false mosaicism detected on chorionic villus sampling can be eliminated.

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Why cytogenetic analysis is important?

Why is karyotyping important in medical genetics?

What are the indications for chromosomal analysis?

What is the importance of cytogenetics in medical science?

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What is the importance of cytogenetics in medical technology?

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