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Flu vaccines are available either as: a trivalent or quadrivalent intramuscular injection (IIV3, IIV4, or RIV4, that is, TIV or QIV), which contains the inactivated form of the virus. a nasal spray of live attenuated influenza vaccine (LAIV, Q/LAIV), which contains the live but attenuated (weakened) form of the virus.
Are quadrivalent flu vaccines safe? Yes. Flu vaccines that protect against four flu viruses have a safety profile similar to seasonal flu vaccines made to protect against three viruses, with similar\u2014mostly mild\u2014side effects.
Two types of influenza vaccine are widely available: inactivated influenza vaccines (IIV) and live attenuated influenza vaccines (LAIV). Traditionally, influenza vaccines (both IIV and LAIV) have been produced to protect against 3 different seasonal influenza viruses (also called trivalent vaccines).
Are all influenza vaccines the same? While all influenza vaccines will protect against the same 4 flu viruses, different influenza vaccines are manufactured differently and different preparations have different indications as licensed by the FDA. In particular, each vaccine is licensed for a specific age range.
The most widely used seasonal influenza vaccine is the trivalent inactivated vaccine (TIV).

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People also ask

Are all influenza vaccines the same? While all influenza vaccines will protect against the same 4 flu viruses, different influenza vaccines are manufactured differently and different preparations have different indications as licensed by the FDA. In particular, each vaccine is licensed for a specific age range.
High-Dose Quadrivalent is a four-component flu vaccine. It is one of three influenza vaccines (along with Flublok Quadrivalent and Fluad Quadrivalent) that is preferentially recommended for people 65 years and older. This preferential recommendation is new for the 2022-2023 season.
TABLE. Influenza vaccines United States, 202122 influenza season* Trade name (manufacturer)PresentationsRouteFlucelvax Quadrivalent (Seqirus)5.0-mL MDVIMHD-IIV4 (high-dose, egg-based vaccine) High-Dose Quadrivalent (Sanofi Pasteur)0.7-mL PFSIMaIIV4 (standard-dose, egg-based vaccine with MF59 adjuvant)16 more rows
Recent observational studies among Medicare beneficiaries 65 years and older found that trivalent Fluad provided greater protection against flu-related hospitalizations and emergency department visits than unadjuvanted standard-dose, egg-based quadrivalent flu vaccine.
High-dose vaccines include four times as much flu virus antigen \u2014 the part of the vaccine that stimulates the immune system \u2014 as standard flu vaccines. This can give older people a higher immune system response against the flu.

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