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Central centrifugal cicatricial alopecia (CCCA) Some people also have hair regrowth when treatment starts early. Early treatment is important because this disease destroys hair follicles. These are tiny pores (or openings) in your scalp from which your hair grows.
CCCA can also result from too much tension on hair follicles from braids, weaves or extensions. But some research suggests that CCCA might be hereditary. Chronic cutaneous lupus erythematosus (CCLE): CCLE describes skin problems caused by lupus erythematosus, an autoimmune disease.
In terms of treating CCCA specifically, many patients can benefit from oral and topical antibiotics, steroid injections to the scalp, and anti-inflammatory medications, said Dr. Taylor.
Generally, cicatricial alopecia is caused by inflammation, which damages the hair follicle. Damage can also stem from a trauma such as a burn or serious infection. The inflammation can involve different types of cells, including lymphocytes, natural killer cells, or several cell types.
High-potency topical corticosteroids can be prescribed as first-line topical treatment (alone or in combination) to treat CCCA. A high-potency topical corticosteroid would be appropriate if applied to the scalp (alone or in combination) daily for at least 4 wk and then tapered to a maintenance dose.

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Central centrifugal cicatricial alopecia (CCCA) is a unique form of scarring alopecia that clinically presents as patches of permanent hair loss on the vertex or crown of the scalp and spreads centrifugally.[1] (See Image.

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