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What does EC80 mean?

With EC50, you can calculate EC whatever, by definition, EC80 is the drug concentration that gives 80% of Emax. In the sigmoid equation, replace E with 0.8*Emax and solve for C, then you will have. EC80=(0.8/(1-0.8))**(1/GAMMA)*EC50.

What is a potent EC50?

In pharmacology, the potency of a compound is expressed as the half-maximal effective concentration (EC50), which refers to the concentration of a drug that induces a response halfway between the baseline and maximum.

Does EC50 measure affinity?

EC50 measurement allows for rank ordering of many unique clones, but may not provide an accurate measure of affinity. It does however, allow for determination of a sub-saturating concentration of rAB that can provide for more accurate determination of rAB affinity in competitive ELISA.

What does a low EC50 mean?

The lower the EC50, the less the concentration of a drug is required to produce 50% of maximum effect and the higher the potency.

What does the EC50 value mean?

EC. 50. The parameter EC50 abbreviates for 'half maximal effective concentration'. In a pharmacological context, this can be the concentration of a drug that is necessary to cause half of the maximum possible effect.

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How is pEC50 calculated?

The pEC50 is defined as the negative logarithm of the EC50. If the EC50 equals 1 micromolar (10-6 molar), the log(EC50) is -6 and the pEC50 is 6.

How do you interpret EC50?

The term "potency" refers to the EC50 value. The lower the EC50, the less the concentration of a drug is required to produce 50% of maximum effect and the higher the potency. The EC10 and EC90 concentrations to induce 10% and 90% maximal responses are defined similarly.

How can I determine an EC90?

ComputingECanythingfrom the EC50 If you know the EC50 and Hill slope (H), you can easily compute the EC80 or EC10 or any other value you want. For example, if the Hill slope equals 1, the EC90 equals the EC50 times nine. If H equals 0.5, the curve is shallower and the EC90 equals the EC50 times 81.

What is an EC80?

The Cox EC80 Flow Processor is a programmable electronic processor, providing total compensation to enhance flow meter accuracy, while extending the linear flow range.

What is EC90 value?

The EC90 was calculated as the concentration of drug that increased the percentage of formazan production in drug treated, virus infected cells to 50% of that produced by drug free uninfected cells on human rhinovirus-2.

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