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The Integrated Research Application System (IRAS) is a single system for applying for the permissions and approvals for health and social / community care research in the UK.
Confirmation of NHS trust Capacity and Capability is the local feasibility procedure undertaken by an NHS Organisation to assess and confirm whether the organisation has the resources, policies and service users required to successfully deliver the research study to time and target.
The Regulations require a person with parental responsibility or a legal representative to provide consent as soon as possible after entry into the trial (see Section 16 of the HRA guidance for further information).
Confirming: Confirming that the Trust has the capacity and capability in place to deliver the study and will deliver the study. This confirmation is given through the mutual confirmation of the contents of the Organisation Information Document for non- commercial studies or sign-off on an agreement.
These are known as Participant Identification Centre (PIC) studies. If a GP practice agrees to be a study PIC then the study team does not have permission to carry out research activity at the practice but general practices can be involved in supporting recruitment to studies by identifying participants.
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A Health Board/ Trust (eg a hospital clinic) identifies potential patients and provides. them with an information pack about a. study taking place in a neighbouring Health.
Confirmation of NHS trust Capacity and Capability is the local feasibility procedure undertaken by an NHS Organisation to assess and confirm whether the organisation has the resources, policies and service users required to successfully deliver the research study to time and target.

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