ADAntihistamineAdministrationForm doc 2025

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They also come in several different forms including tablets, capsules, liquids, syrups, creams, lotions, gels, eyedrops and nasal sprays.
However, some generally considered to be among the most powerful prescription antihistamines include Desloratadine (learn more about how it compares to Loratadine in our guide) and Xyzal. For over-the-counter antihistamines, Cetirizine and Fexofenadine are very effective second-generation choices.
Cetirizine is the only second-generation H1 antihistamine approved for intravenous use. Compared with IV diphenhydramine, IV cetirizine has an improved safety profile including less sedation, fewer contraindications, fewer warnings and precautions, and less risk in the elderly population.
Antihistamine medications are generally administered orally in a tablet dosage form. Intravenous (IV) and intramuscular (IM) administration are also possible, reserved chiefly for in-patient usage for the treatment of specific conditions.
Product Overview. This liquid allergy medicine helps relieve kids indoor and outdoor allergy symptoms for a full 24 hours. Each 5 mL of this allergy syrup contains 5 mg of cetirizine HCl antihistamine to help treat allergy symptoms such as runny nose, sneezing, and itchy nose and throat.
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Antihistamines for Allergies ZYRTEC products, for instance, contain cetirizine, which is an H1 blocker. Other examples of H1 antihistamines for allergies include2: Azelastine.
Unlike other antihistamines, hydroxyzine may help boost serotonin levels in the brain to treat anxiety. Good to know: Hydroxyzine can treat many different types of anxiety, but its used most often for generalized anxiety disorder especially when its contributing to insomnia.

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