Pharmacist's Manual - SECTION IX-XIV - DEA Diversion Control 2025

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The DEA Form 41 shall list the controlled substance or substances which the registrant desires to dispose. (C) By destruction in the presence of an agent of the Administration or other authorized person.
Under 21 CFR 1305.03, the completion of DEA Form 222 is required for each distribution of a schedule I or II controlled substance.
Talk to your pharmacist to ensure they will accept the transfer of your prescription, as pharmacists can legally refuse to make the transfer. Also, certain medications do not allow you to transfer to a different pharmacy including Adderall, Concerta, Oxycontin, Percocet, and Vicodin.
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Some prescriptions cant be transferred. They also arent eligible for refills, so your healthcare provider will need to give you a new prescription every time you need it. Some common examples include Adderall (amphetamine salt combo), Concerta (methylphenidate ER), and Norco (hydrocodone/acetaminophen).
Privacy Act Information for DEA Form 106: AUTHORITY:Section 301 of the Controlled Substances Act of 1970 (PL-513).PURPOSE:Report theft or loss of Controlled Substances.5 more rows
For example, for a registrant using a business address instead of a name, the DEA number might look like F91234563. In some cases, multiple people (possibly including interns or nurses) are prescribing under the supervision of a more senior prescriber.
The Pharmacy Manual guides pharmacy providers to the regulations and the administrative and billing instructions they need.
DEA Form 41 is used to request permission from the DEA to destroy controlled substances. The only time University researchers use Form 41 is after controlled substances have been lost due to accidentally spilling or breaking a container.

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