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How is blood spot testing done?

Patients prick blood from a fingertip, and blot it onto the card. Each card contains five 13 millimeter circles, and each circle holds about 75-80 microliters of blood. The blood sample dries in a fibrous matrix and is shipped to the telemedicine lab for review. At the lab, technicians punch the five spots out.

How is newborn Bloodspot screening done?

They will use a small device to prick your babys heel to get the blood. This is uncomfortable and can make your baby cry for a moment, so they may need a cuddle or a feed afterwards to reassure them. The test is normally done by the time your child is five days old.

What is blood spot testing for neonatal screening?

What is blood spot screening? Blood spot screening is the process of testing babies to determine whether they are at risk for over 60 rare conditions that may make them sick before symptoms appear. Often, it is the only way to tell if newborns are affected, since these conditions are generally not detectable at birth.

Why is dried blood spot test in newborns done?

Dried blood spots contain information (including genetic information) that may be useful for study- ing birth defects and diseases. DBS might also be used to evaluate the effects certain infections or substances (such as lead) have on a developing baby.

What are the main conditions that can be detected from the newborn bloodspot screen?

Currently, conditions that can be identified through newborn bloodspot screening include phenylketonuria (PKU), congenital hypothyroidism, cystic fibrosis (CF) and approximately 22 other metabolic conditions that affect fat or protein metabolism (see full list at Appendix 1).

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