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What does it mean when your AST and ALT levels are high?

If you have high levels of AST and/or ALT, it may mean that you have some type of liver damage. You may also have an AST test as part of a group of liver function tests that measure ALT, and other enzymes, proteins, and substances in the liver.

What level of AST is concerning?

An AST/ALT ratio higher than one (where the AST is higher than ALT) means you may have cirrhosis. An AST/ALT ratio higher than 2:1 (where the AST is more than twice as high as the ALT) is a sign of alcoholic liver disease.

What level of AST indicates liver damage?

A normal AST:ALT ratio should be 1 in 92% of patients, and 2 in 70%. AST:ALT scores 2 are, therefore, strongly suggestive of alcoholic liver disease and scores

What does a high AST level mean?

An increased AST level is often a sign of liver disease. Liver disease is even more likely when the levels of substances checked by other liver blood tests have also increased. An increased AST level may be due to any of the following: Scarring of the liver (cirrhosis) Death of liver tissue.

What causes high AST and ALT levels?

Chronic alcohol consumption, drugs, non-alcoholic steatohepatitis (NASH) and chronic viral hepatitis are common causes associated with raised ALT and AST. In chronic viral hepatitis, the elevation of liver enzyme may not correlate well with the degree of liver damage.

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