Flu shot form 2025

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Fluzone High-Dose flu vaccine contains four times the antigen as standard dose flu vaccines. In the United States, Fluzone High-Dose vaccine is approved for people 65 years and older. It is one of three flu vaccines that are preferentially recommended for people 65 years and older.
Fluzone is approved for use in persons 6 months of age and older. Flublok is approved for use in persons 18 years of age and older. Fluzone High-Dose is approved for use in persons 65 years of age and older.
Injection site Deltoid: Give in the central and thickest portion of the deltoid muscle above the level of the armpit and approximately 23 fingerbreadths (~2) below the acromion process (see diagram 1). To avoid causing an injury, do not inject too high (near the acromion process) or too low.
Flu vaccines available in the US include: High-dose, egg-based influenza vaccine (which has 4 times the antigen compared with a standard-dose inactivated influenza vaccine) Standard-dose, adjuvanted egg-based influenza vaccine.
1 Use a needle long enough to reach deep into the muscle. Infants age 6 through 11 mos: 1; 1 through 10 yrs: 11, and children and adults 11 years and older: 11. 2 With your left hand*, bunch up the muscle. 3 With your right hand*, insert the needle at a 90 angle to the skin with a quick thrust.

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In addition to its characteristics born of recombinant technology, Flublok also contains 3x the hemagglutinin (HA) antigen content of standard-dose flu vaccines, which has been associated with higher immunogenicity when compared to standard-dose flu vaccines.
Flublok is similar to Fluzone High-Dose in that it contains more flu antigen, although Flublok contains only three times (rather than four times) the amount of flu antigen as the standard vaccine. But dont think that means its less effective than the other high-dose vaccine.
Recombinant flu vaccine (brand name: Flublok) is one of the three vaccines that are preferentially recommended for people 65 years and older because a review of existing studies suggested that, in this age group, these vaccines are potentially more effective than standard dose unadjuvanted flu vaccines.

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