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Treatments include eye drops, ointments, and special eye patches or contact lenses that stop your eyelid from rubbing against your cornea. If you have severe corneal erosions or corneal scarring, you may need a surgical treatment, like laser eye surgery or a corneal transplant.
What are fibroblasts and what is their function?
Definition. 00:00. Apoptosis is the process of programmed cell death. It is used during early development to eliminate unwanted cells; for example, those between the fingers of a developing hand. In adults, apoptosis is used to rid the body of cells that have been damaged beyond repair.
What is fibroblast apoptosis?
Fibroblast apoptosis is a critical component of normal repair and the acquisition of an apoptosis-resistant phenotype contributes to the pathogenesis of fibrotic repair.
Do fibroblasts undergo apoptosis?
The involvement of specific fibroblast lineages may have particular relevance to diseases characterized by excessive fibrosis and scarring such as scleroderma, keloids, graft-versus-host disease, and pulmonary fibrosis.
What is apoptosis and what does it do?
Fibroblasts cultured in a contractile, mechanically relaxed collagen matrix undergo apoptosis in a time-dependent manner as described earlier (Fluck et al, 1998), and in order to further investigate this phenomenon we studied the role of distinct integrins in apoptosis induction in fibroblasts.
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