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Treatment of MMN: Present and Future Treatment with IVIG has been shown to be beneficial in randomized controlled trials. Cyclophosphamide has been reported to be effective, but its toxicity precludes long-term use, which is usually necessary in patients with MMN.
Typically, MMN is slowly progressive, resulting in asymmetrical weakness of a patients limbs. Patients frequently develop weakness in their hand(s), resulting in dropping of objects or sometimes inability to turn a key in a lock.
Each person diagnosed with MND will experience the disease differently. Symptoms may occur in a different order and may occur at a different rate. For some people, symptoms can progress overtime while others can experience more rapid progression.
Multifocal motor neuropathy is a progressive disorder, this means that the signs and symptoms tend to worsen slowly over time. The main symptom is progressive muscle weakness of the arms and legs. Unlike other neurological disorders affecting the arms and legs, there usually is not any sensory deficits.
If you have MMN, youll most likely notice the first symptoms in your hands and lower arms. Your muscles may feel weak and cramp up or twitch in a way you cant control. It may start in specific parts of the arm or hand, like the wrist or finger. Usually the symptoms are more severe on one side of your body.
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MMN is a disease that progresses steadily. Despite the progression of the disease, those affected tend to have a normal life expectancy. The underlying pathological process of MMN still remains unclear; however it appears to be immune-mediated, with GM1-specific IgM antibodies playing an important role.
You may have trouble lifting your foot if MMN weakens muscles in that foot. This can make it difficult to walk. If MMN affects your dexterity. Ability to perform tasks, especially with the hands.

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