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The Animal Study Protocol, or the IACUC protocol, is a detailed description of the proposed use of animals prepared by the researcher for IACUC review and approval. Activities involving animals in research, testing, and teaching can begin only after they have been reviewed and approved by the IACUC.
An institutional animal care and use committee (IACUC) is required by federal regulations for most institutions that use animals in research, teaching, and testing. The IACUC has a key oversight role, including the review and approval of animal use activities, and inspection of animal facilities.
An animal care and use program (hereafter referred to as the Program) comprises all activities conducted by and at an institution that have a direct impact on the well-being of animals, including animal and veterinary care, policies and procedures, personnel and program management and oversight, occupational health and
IACUC responsibilities include: Review, at least semiannually, the institutions program for the humane care and use of animals; Inspect, at least semiannually, the institutions animal facilities (including satellite facilities); Prepare reports to the Institutional Official (IO) of the IACUC evaluations;
Animal - Any live, vertebrate animal used or intended for use in research, research training, experimentation, or biological testing or for related purposes. A study, that involves the eggs and embryos of vertebrates, is not covered until those eggs hatch. However, larval forms of fish and amphibians are covered.
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The Institutional Animal Care and Use Committee is the body that provides oversight and ensures appropriate review of the use of vertebrate animals in teaching, testing, and research. The committee composition is generally designed to be broad enough to represent both scientific and nonscientific interests.
IO; the person in the organization having the administrative and operational authority to commit institutional resources to ensure that the animal care and use program complies with requirements of the Animal Welfare Act Regulations, PHS Policy, and VA Policy.
Ensuring animal welfare is a human responsibility that includes consideration for all aspects of animal well-being, including proper housing, management, nutrition, disease prevention and treatment, responsible care, humane handling, and, when necessary, humane euthanasia.

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