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Pyruvate enters mitochondria from the cytoplasm and undergoes oxidative decarboxylation i.e., removal of a carboxyl group, to produce acetyl CoA, CO2, and NADH. 1 NADH molecule gives its electrons to the electron transfer chain, and through the process of oxidative phosphorylation, 3 ATP molecules are produced.
13. Why is the 4-carbon compound generated in the breakdown of citric acid the only permanent compound in the Krebs cycle? It is regenerated at the end of each complete turn of the cycle. Electron Transport (pages 228-229) 14.
The 3-carbon pyruvate molecule made in glycolysis loses a carbon to produce a new, 2-carbon molecule called acetyl CoA. The carbon that is removed takes two oxygens from pyruvate with it, and exits the body as carbon dioxide (CO 2\u200bstart subscript, 2, end subscript).
What is the energy tally from 1 molecule of pyruvic acid during the Krebs cycle? It is 4 NADH molecules, 1 FADH2 molecule, and 1 molecule of ATP.
Pyruvate\u2014three carbons\u2014is converted to acetyl CoA, a two-carbon molecule attached to coenzyme A. A molecule of coenzyme A is a necessary reactant for this reaction, which releases a molecule of carbon dioxide and reduces a NAD+ to NADH.

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The eight steps of the citric acid cycle are a series of redox, dehydration, hydration, and decarboxylation reactions. Each turn of the cycle forms one GTP or ATP as well as three NADH molecules and one FADH2 molecule, which will be used in further steps of cellular respiration to produce ATP for the cell.
During the Krebs cycle, energy stored in pyruvate is transferred to NADH and FADH2, and some ATP is produced.
Instead, the pyruvic acid breaks down to acetylcoenzyme A, which enters the Krebs cycle and the electron transport system and is eventually processed to form water plus carbon dioxide plus a large amount of ATP.
All told, the Krebs cycle forms (per two molecules of pyruvic acid) two ATP molecules, ten NADH molecules, and two FADH2 molecules.
The Krebs Cycle releases energy from Acetyl\u2013CoA, but the cellular challenge is to release the energy gradually and in useable forms....Steps in the Krebs Cycle Step 1: Citrate synthase. ... Step 2: Aconitase. ... Step 3: Isocitrate dehydrogenase. ... Step 4: \u03b1-Ketoglutarate dehydrogenase. ... Step 5: Succinyl-CoA synthetase.

why is the 4 carbon compound generated in the breakdown