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In this video, I will define the beyond use date or BUD and provide an example of how to calculate the BUD. The beyond use date is when a vaccine or diluent must be used before its expiration date. While all vaccine and diluent have an expiration date, only some vaccines have a BUD. ♪ Information about the BUD can be found in the manufacturers product information. Providers may encounter instances when a BUD will need to be calculated. The first is when a lyophilized vaccine is mixed with its diluent, or reconstituted, and then not used immediately. For example, a patient or parent refuses vaccine after it is prepared. The Immunization Action Coalition or IAC has a table summarizing the BUD for lyophilized vaccines and their diluents. Another exception is related to multidose vials of vaccine. Most multidose vials may be used until the expiration date printed on the vial unless contaminated or compromised in some way. However some multidose vials have a specified timeframe for use on