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[MUSIC PLAYING] Hello, my name is Dave. I work at Waters Corporation as a development scientist. Im going to give a brief description of what is meant by the term resolution when it comes to mass spectrometry. Perhaps the most common usage of the term resolution relates to optical devices, such as cameras or television screens. In that case, the resolution is often defined by the number of pixels the screen is made up of, which essentially is a definition of how detailed a picture can be captured or displayed. The premise is similar in mass spectrometry. Here the resolution is a measure of the ability to separate ions of one mass from those of another. So essentially, its a measure of how detailed a spectrum the mass spec can generate. For low resolution, mass spectrometers such as quadrupole instruments, the resolution is generally defined as the full width of the peak at half its maximum height, commonly abbreviated to FWHM. This value is set to approximately 0.7 amu and is not de
