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Light itself has an intrinsic grain. And that is, you can take an image at very high resolution, but if you keep blowing it up and magnifying it more and more, you dont actually get more information. And Id like to talk about why that is, because this has limited traditional forms of microscopy with a limit thats related to the diffraction of light. Ill explain what that is. And this diffraction limit ultimately leads us to an irresolvably small spot of light, which is based on something known as the point spread function. That limits the resolution of traditional forms of microscopy. So to begin, I think we have to talk about why light doesnt behave in a way that would just allow infinite magnification. And that is, for most of us, anyone whos held a laser pointer, you get the impression that light travels in straight lines. And that should be very straightforward to understand where light goes, and the best example of this for imaging is the simplest of all imaging devices, th
