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(soft music) - Variability is what I would expect to see in a biological system because even if you have completely identical genotypes of say, bacterial cells, there could be subtle differences in the timing of expression of genes within those cells to give these identical genotypes different, what are called, phenotypes, different traits, even though they have exactly the genotype. So the point is that variability is something we see in the natural world all of the time, it is just there. The rule of thumb is if there is variation in your experiment that is seemingly random, you can correct for it by increasing your sample size. So if you have a few samples, the effect of random variation is gonna have a large impact on the result that you ultimately report. But if you have a huge pool of samples, those random fluctuations are gonna kinda cancel each other out across all the samples. But it will not correct for systemic biases. So thats things like instrumentation bias. So if you h