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Voiceover: So what makes a cell thats located inside of your nose responsible for smelling, say, a slice of pizza look and act differently from a cell that lines your gut and is responsible for absorbing the nutrients from that pizza? They have the exact same DNA so the differences cant be attributed to that fact alone. The answer actually lies in the expression of that DNA, which genes are actively transcribed and which ones arent and there are several ways in which gene regulation occurs at the level of transcription and so were going to be talking about the main ones here. Now lets draw out a hypothetical gene here and associated with this gene is a sequence upstream so towards the three prime region of the antisense strand, also called the template strand. And this sequence is called the promoter and there is another sequence in between the promoter and the gene called the operator. The operator is the sequence of DNA to which a transcription factor protein combined and the p