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In this video, the tutorial demonstrates how to encrypt a PDF document using Nuance Power PDF. If you do not have Nuance Power PDF, you can install it using the Oxford installer program or request a free copy from your IT department. To encrypt the PDF, go to the security section, change the security method to password security, and select strong AES-256 encryption. Set the document to only open with a password, enter a strong password of at least 12 characters, confirm it, and you are done.