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The text discusses the importance of disease monitoring, specifically focusing on checking viral load levels through standardized testing every three months. It emphasizes the challenge of interpreting slight changes in PCR results, especially when patients fluctuate between undetectable and quantifiable levels. This uncertainty causes alarm to patients, particularly concerning those who transition from being undetectable to detectable. The text highlights the need to assess for true changes in viral load levels to determine the significance of the fluctuations.