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so welcome everyone to these webinar and submissions of parallel distribution notifications for centralized products my name is Regina Rojo Im scientific specialist in the procedures office and team lead for the parallel distributions team so weve organized this webinar basically to give you an overview on how to submit the initial notifications and annual updates via Iris to discuss the most frequently made mistakes and also provide some advice on requirements for particular types of products so before we start I just wanted to remind everyone that this webinar will be recorded and the video will be available in our website so we will start with some housekeeping rules for the day so please mute yourselves make sure that your microphone is muted because we have a high number of participants so unless youre given the floor to speak please make sure that you close your phones as to include any questions in the chat you can do that during any time during the presentations we will be