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[Music] hello im dr anil guri im a consultant in reproductive medicine surgery and assisted conception at fertility plus and the hamilton fertility center in london so today im going to talk to you about a slightly older paper but it does give a insight into a very important topic what is the impact of age on euploidy in simple terms does age have a negative impact on abnormal embryos and increase in aneuploidy and so this paper was a paper with a large number of embryos which are biopsied using a slightly older technology and they looked at maternal age its effect on euploidy of a large cohort of embryos at present what we know is that an abnormal embryo or aneuploidy is common in human embryos and in fact as humans we produce a huge number of abnormal embryos fortunately very few of them will implant and thus at the end product the chance of having an abnormal baby is extremely low many of the chromosomal abnormalities results mainly from meiotic errors during oocyte generation s