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To reduce the size of a 48MB brochure PDF, use the "Save As" function and select "docHub PDF." Optimize for fast web view, remove illustrator editing capabilities, and go to compression. Choose average downsampling, set both to 300 PPI, automatic JPEG compression, and high-quality maximum. In Marks and bleeds, select trim marks, then save the PDF. The final size will be 5MB with high quality. Subscribe to the YouTube channel for more tutorials and support by purchasing courses, templates, and presets. Links in the description. Thank you for your support.