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in the previous video we understood the concept of nucleic acid hybridization and probes we learned that the basis of nucleic acid hybridization is the complementary base pairing letamp;#39;s now understand what do we mean by blotting blot refers to the membrane on which biological molecules such as proteins and nucleic acids are absorbed or immobilized and the process of transferring these molecules from a gel to a membrane followed by their detection on the membrane is known as blotting when the macromolecule involved is DNA the technique is known as southern blotting southern is the last name of the scientist who first blotted DNA he is Sir Edwin Mello southern by analogy blotting involving RNA is known as northern blotting and for protein this technique is known as Western blotting both southern and northern blotting techniques are based on nucleic acid hybridization letamp;#39;s now study southern blotting and detail southern blotting has been used for the detection of a specifi
