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youre ready um you can go ahead great lets get started thanks everyone for calling in full disclosure I am NOT a true expert on transcripts Im just going to give you some background that I picked up while doing gene and variant curation local lab and I really do encourage you to check out the webinar recording theyll refer to in this presentation what it is available and the slides from NCBI and amble EBI so this is the outline of my talk today and I should have enough time for questions but feel free to interrupt me as we go if you have a question so Im going to start with what I transcript curation is important and Im going to illustrate this by using examples from the human loss domain apologies like jennyline i am largely doing a lot of hearing loss duration so most of my examples if not all them are hearing loss and then im going to talk to you about transcript annotation bodies and the different transcript types of transcripts that you will see when youre doing your cura