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so hi my name is Brian katfoe welcome to this weeks ask Brian part of our weekly newsletter you can sign up for the newsletter theres a link in the video description below theres also a link to ask a question and if you had a chance subscribe to the YouTube channel so Im going to answer a question this week thats relevant to some work developed at Johns Hopkins biostatistics and someone asked what is GE II okay so this is kind of a complicated topic and Ill give some references at the end where you can you know build on this so if Im going to give a very brief overview of whats going on here in it and you do to really do this topic justice youll have to get a book or take a course or something like that okay so ge was developed by Scott Ziegler and chameleon two very celebrated professors in the department of biostatistics Connie has since moved on his president of a university now Scott is still at Johns Hopkins biostatistics anyway in this work as I would say easily you kno