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Voiceover: In this video, I want to talk about how neurotransmitter is released at the synapse. In the last video, we went over the structure of a typical chemical synapse with an axon terminal like Ive drawn here in green that have synaptic vesicles full of neurotransmitter and we talked about how on the postsynaptic membrane of the target cell, there are receptors for those neurotransmitter molecules, but the question is, how do the neurotransmitter molecules get out of these synaptic vesicles in the axon terminal to cross the synaptic cleft and bind to their receptors? To understand neurotransmitter release, we need to talk about this new type of ion channel. This is a voltage gated calcium channel. We talked about voltage gated sodium and potassium channels when we talked about the action potential that at the axon terminal there are these voltage gated calcium channels that play a big role in neurotransmitter release. When the action potential comes down the axon and docHubes th
