PRIOR AUTHORIZATION DRUG ATTACHMENT FOR HEPATITIS C AGENTS, F-01247 2026

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  1. Click ‘Get Form’ to open it in the editor.
  2. Begin with SECTION I – MEMBER INFORMATION. Enter the member's name, ID number, and date of birth clearly.
  3. Proceed to SECTION II – PRESCRIPTION INFORMATION. Fill in the date the prescription was written, prescriber's name, National Provider Identifier, address, and phone number.
  4. Indicate the member’s proposed hepatitis C drug treatment regimen by listing the drug names, whether currently taking them, daily doses, and expected duration.
  5. In SECTION III – CLINICAL INFORMATION, provide diagnosis codes and descriptions. Ensure to attach relevant medical records as specified.
  6. Complete any additional questions regarding previous treatments and conditions that may affect drug usage.
  7. Finally, sign in SECTION IV – AUTHORIZED SIGNATURE and include any additional information in SECTION V if necessary.

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BACKGROUND: Mavyret, Zepatier, and Vosevi are FDA-approved to treat chronic hepatitis C in patients without liver impairment or with mild liver impairment (Child-Pugh A).
With this approval, MAVYRET is the first and only DAA therapy approved to treat patients with acute HCV in eight weeks with a 96% cure rate. HCV is a highly infectious blood-borne disease affecting the liver. People recently infected, or those with acute HCV, may not have symptoms.
Ledipasvir/sofosbuvir (Harvoni) Ledipasvir inhibits HCV NS5A protein, which is required for viral replication. Sofosbuvir is an inhibitor of HCV NS5B RNA-dependent polymerase. The oral combination is indicated for treatment of adults with chronic hepatitis C infection with genotype 1, 4, 5, or 6.

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Mavyret, Vosevi, and Epclusa are all FDA-approved for the treatment of chronic (long-lasting) hepatitis C virus (HCV) genotype 1, 2, 3, 4, 5 or 6 infection without cirrhosis or with compensated cirrhosis (Child-Pugh A). In June 2025, Mavyret was also approved by the FDA to treat acute (recently infected) HCV.
There are now three pan-genotypic DAA regimens listed on the PBS: sofosbuvir plus velpatasvir, glecaprevir plus pibrentasvir, and sofosbuvir plus velpatasvir plus voxilaprevir. The first-line regimens for treatment-naive people living with hepatitis C are sofosbuvir plus velpatasvir or glecaprevir plus pibrentasvir.
When taken exactly as prescribed, both drugs are highly effective at curing this disease. Depending on your condition, you may only have to take Mavyret for 8 weeks compared with 12 weeks for Epclusa. However, your doctor may prescribe Epclusa if you have severe liver disease.
Medically reviewed by Leigh Ann Anderson, PharmD. Last updated on June 15, 2025. The newest drugs for the treatment of hepatitis C include Mavyret (glecaprevir and pibrentasvir), Vosevi (sofosbuvir, velpatasvir, and voxilaprevir), and Epclusa (sofosbuvir and velpatasvir).

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