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Researchers reported Monday theyve found a gene that might help explain why so many people find alcohol irresistible, and why others are able to abstain from more than a drink or two. The gene is called beta-Klotho, and it seems to act as a brake on drinking alcohol.
Whalen (1983) described four types of wives of alcoholics viz. suffering Susan, controlling Catherine, wavering Winifred and punitive Polly, where the disturbed personality of the wife was a docHub contributor to alcoholism in her husband.
Mutations in the Gabrb1 gene promote alcohol consumption through increased tonic inhibition.
Context Innate differences in opioid neurotransmission are hypothesized to influence abuse liability of alcohol. In humans, a variant of the -opioid receptor gene (OPRM1A118G) increases receptor affinity, alcohol-induced euphoria, and risk for alcohol use disorders.
2.1 OPRM1 A118G. OPRM1 is a key candidate gene since -endorphin and the opioid receptor have been shown to play an important role in the rewarding or reinforcing effects of alcohol (Thorsell, 2013).
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The genes with the clearest contribution to the risk for alcoholism and alcohol consumption are alcohol dehydrogenase 1B (ADH1B) and aldehyde dehydrogenase 2 (ALDH2; mitochondrial aldehyde dehydrogenase), two genes central to the metabolism of alcohol (Figure 1)20.
Al-Anon is one of the oldest and largest support groups in the world for friends and family of alcoholics.
It is no mystery that alcoholism can destroy a persons life. However, it is important to remember that the damage caused by alcohol abuse can affect the mental health of everyone in the addicts life. From depression and anxiety to PTSD, alcoholics family members are susceptible to a range of mental illnesses.

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