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Postmortem Biochemical Estimations in Cases of Fatal Hypothermia

Postmortem Biochemical Estimations in Cases of Fatal Hypothermia 2025

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The document presents a study on postmortem biochemical estimations in cases of fatal hypothermia, focusing on the levels of catecholamines (adrenaline and noradrenaline) and volatile substances (such as acetone and ethanol). It analyzes four cases of fatal hypothermia compared to 12 control cases with varying durations of agony. The findings indicate a significant predominance of noradrenaline in hypothermia cases, especially those with longer agony, while adrenaline levels were higher in cases with shorter agony. The study suggests that combined analysis of catecholamines and volatile substances can aid in diagnosing fatal hypothermia, although variations and overlapping results pose challenges.

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What are the post mortem changes in hypothermia?

In general, autopsy findings of hypothermia are as follows: gastric mucosal hemorrhagic spots (Wischnewski spots), differences in the color of the left and right heart blood, soft blood clots, chicken clots in the heart and large blood vessels, lungs without edema, and a large amount of retention [9].

What are Wischnewsky spots in fatal hypothermia?

Wischnewsky spots (WS) are described as multiple oval or point-like hemorrhages of the gastric mucosa that are suggestive of fatal hypothermia [1]. WS are also observed in cases of chronic alcohol abuse and diabetic ketoacidosis (DKA), accompanied by a black esophagus (acute esophageal necrosis) [2,3,4].

What are necropsy findings in fatal hypothermia cases?

The best diagnostic signs seem to be purple skin and oedema in face and ears, stomach erosions, degenerative foci in myocardium and high concentration of catecholamines in the .

What is necropsy findings?

Put simply, a necropsy is the examination of an animal after death. The purpose of a necropsy is typically to determine the cause of death, or extent of disease. This involves a careful process of dissection, observation, interpretation, and documentation.

What are the post mortem findings in hyperthermia?

Findings may include cerebral edema, visceral petechial hemorrhages, subendocardial hemorrhages, and hepatocyte necrosis. The diagnosis should be based on a history of exposure to a hot environment and on the reasonable exclusion of other causes of hy- perthermia.