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What is the function of Pou1f1?

Pou1f1 autoregulates its own expression (2,3) and the expression of the three signature hormones [ (Gh), prolactin (Prl) and thyroid-stimulating hormone beta subunit (Tsh)]. As such, Pou1f1 serves essential functions in the differentiation and proliferation of somatotropes, lactotropes and thyrotropes.

What is the pituitary specific transcription factor 1?

The pituitary-specific transcription factor Pit1 plays a key role in pituitary gene expression and development. Pit1 is found only in a subset of cell types within the anterior pituitary, even though the five major cell types arise from a common lineage that lacks Pit1 (132).

What is PIT1?

Pit-1 (pituitary-specific transcription factor-1) is a pituitary-specific transcription factor that is responsible for the development of somatotrophs, lactotrophs, and thyrotrophs in mammals.

What does PIT mean for taxes?

What Is the Personal Income Tax (PIT)? Personal Income Tax (PIT), also known as individual income tax, is a tax on employee earnings. According to the IRS, earned income is money earned as an employee or as the owner of a business or farm.

What is a PIT1 pituitary adenoma?

PIT1-positive adenomas (PIT1-PAs), constituted by somatotroph, lactotroph, thyrotroph and plurihormonal adenomas, are usually functional tumours that produce (GH), prolactin (PRL) and thyrotropin (TSH), and lead to systematic endocrine disorders, like acromegaly and hyperprolactinemia [5, 6].

What is PU-1 transcription factor?

PU. 1, encoded by the Spi1 gene, is an ETS-family transcription factor with multiple roles in hematopoiesis. It is a lineage-specifying transcription factor that positively regulates many genes in the macrophage, granulocyte, dendritic-cell and B-cell lineages.

What is pituitary-specific positive transcription factor 1?

PIT1 is a pituitary-specific transcription factor responsible for pituitary development and hormone expression in mammals and is a member of the POU family of transcription factors that regulate mammalian development.

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PIT-1 2025

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What is the function of Pou1f1?

What is the pituitary specific transcription factor 1?

What is PIT1?

What does PIT mean for taxes?

What is a PIT1 pituitary adenoma?

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What is PU-1 transcription factor?

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