Potentially Hazardous Biological Agents Risk Assessment Form (6A) 2025

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Biosafety Risk Assessment, which helps to identify the probability and consequences of infection, is used to ensure that all people potentially exposed to biohazards have an awareness of the potential risk.
Potentially Hazardous Biological Agents (PHBAs) include microorganisms (including bacteria, viruses, viroids, prions, rickettsia, fungi and parasites) and recombinant DNA technologies. Hazardous materials include hazardous chemicals, devices and radiation.
The biological risk assessment process is used to identify the hazardous characteristics of an infectious or potentially infectious agent or material, if known; the activities that can result in a persons exposure to an agent; the likelyhood that such exposure will cause a laboratory associated infection (LAI); and
If you work in a lab that is designated a BSL-1, the microbes there are not known to consistently cause disease in healthy adults and present minimal potential hazard to laboratorians and the environment. An example of a microbe that is typically worked with at a BSL-1 is a nonpathogenic strain of E. coli.
Hazardous biological agents (HBAs) can be defined as any microorganism, cell of plant, animal or human origin, cell culture, human endoparasite, including those that have been genetically modified, which may cause infection, allergy, inflammation, toxic reaction, malignan-cy or otherwise create a hazard to human
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Biological Agents are classified into four risk groups - Groups 1, 2, 3 and 4. Under the classification system, Group 1 agents are the least hazardous whilst Group 4 are the most hazardous.
Some biological agents are carcinogens and can cause cancer. Some biological hazards such as humans and animal tissues, cancer cells and cell lines may contain cancer viruses.
The risk assessment should include considerations about the hazards (e.g., biological agent), the specific processes and procedures, existing control measures, the facility and testing environment, and the competency of the testing personnel.

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