Anesthesia for Temporal Lobe Epilepsy 2025

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The most common surgical procedure for epilepsy is the removal of a small portion of the temporal lobe during a procedure called a temporal lobe resection. More than 70 percent of people who have this surgery at NYU Langone become seizure-free or enjoy a marked improvement in seizure control.
anaesthetic agents. The barbiturates (thiopental, methohexital, and pentobarbital) and propofol are well established as agents for the treatment of refractory status epilepticus.
Approximately 70% of people who undergo a temporal lobe resection have a positive result. A positive result includes being free from seizures or having only rare disabling seizures.
What Is a Temporal Lobectomy? A temporal lobectomy, or temporal lobe resection, is a neurosurgical procedure that removes the front part of the temporal lobe of the brain to treat drug-resistant epilepsy. Each person has two temporal lobes, located beneath the skull on the side of the head in the temple region.
For patients with MTLE, the most effective AEDs are those used to treat focal epilepsies such as carbamazepine, oxcarbazepine, levetiracetam, lamotrigine, and topiramate. [41] These agents can be monotherapy or, more often, in combination to achieve adequate seizure freedom.
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Overall, the prognosis for people with drug-resistant medial temporal lobe epilepsy includes a higher risk for memory and mood problems, lower quality of life, and an increased risk for sudden unexpected death in epilepsy (SUDEP). If surgery can be done to control seizures, these risks and problems can be improved.
Anterior temporal lobectomy: what to expect This operation is performed under general anesthesia, and takes about 4-5 hours. A question-mark-type incision is made starting just in front of the ear and extends backwards above the ear and then forwards toward the temporal area.

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