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Cold Chain Management Vaccines should be maintained within the recommended temperature range of 35F (2C) to 45F (8C). The loss of vaccine effectiveness is cumulative and cannot be reversed.
The Cold Chain is the system of transporting and storing vaccines within the temperature range of 35F (2C) to 45F (8C). The cold chain begins when vaccine is manufactured, moves through to the state distribution center and ends with the local immunization provider at the time of administration.
If the error is discovered while the patient is still in the office, you can give another pediatric dose (i.e., the other half dose). If the error is discovered after the person has left the office, then the patient should be revaccinated with a full age-appropriate dose as soon as feasible.
Follow these steps for all CCBs Isolate the vaccines and place a sign on the vaccine refrigerator Do not use or discard vaccines until further notice. Download and complete the Cold chain breach report form as soon as possible, complete and email to the department. Continue to store vaccines between +2C to +8C.
Follow the cold chain breach (CCB) protocol steps: Immediately isolate the affected vaccines and mark as DO NOT USE. DO NOT DISCARD ANY VACCINES. Keep vaccines refrigerated between +2C and +8C. Be prepared to transfer the affected vaccines into temporary monitored vaccine storage.
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Temperature monitoring should follow the Green Book guidance which gives details of the four Rs: Read, Record, Reset, React. The person making the recording of the fridge temperature should: record temperature at least once every day during the working week and sign the temperature record sheet.

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